Trospium chloride
Trospium chloride
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Systematic (IUPAC) name |
3-(2-hydroxy-2,2-diphenylacetoxy)spiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-1'-ium chloride |
Clinical data |
AHFS/Drugs.com |
monograph |
Pregnancy cat. |
? |
Legal status |
? |
Pharmacokinetic data |
Protein binding |
50–85% |
Half-life |
20 hours |
Identifiers |
CAS number |
10405-02-4 |
ATC code |
G04BD09 |
PubChem |
CID 107979 |
DrugBank |
APRD00393 |
ChemSpider |
10482307 Y |
UNII |
1E6682427E Y |
ChEMBL |
CHEMBL1201344 |
Chemical data |
Formula |
C25H30ClNO3 |
Mol. mass |
427.964 g/mol |
SMILES |
eMolecules & PubChem |
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InChI=1S/C25H30NO3/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26/h1-6,9-12,21-23,28H,7-8,13-18H2/q+1/t21-,22+,23+ Y
Key:OYYDSUSKLWTMMQ-JKHIJQBDSA-N Y
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Y(what is this?) (verify)
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Trospium chloride (INN) is a muscarinic antagonist urinary antispasmodic. It has been developed and patented by Robert Pfleger (Germany) and is sold under the brand name Sanctura in the US, Tropez OD in India,Trosec in Canada, Regurin and Flotros in the United Kingdom and Spasmex in Germany, Russia, Turkey, Argentina, Chile and Israel. The drug is used for the treatment of Overactive Bladder.
It is available in Egypt under the brand name Trospikan by Hikma pharma.